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At first, they thought it was fun not to go to work or school, then it became a game as to who could get away with not abiding by the rules. As the years progressed, it turned to despair as everyone was forced to stay in their homes.
There were virtual classrooms and offices everywhere, like the holograms in the science fiction television programmes from the 20th century. They became so real, eventually
no-one saw a difference, or wanted to. They were safe in their own little world as no two worlds met, mingled, or merged. You could exercise, shop, and meet up with virtual people from the comfort of your sitting room at the push of a button.
Procreation was by mail order, sperm samples being collected by drones and delivered to huge conglomerate establishments for analysis and elimination. Pregnancy was in a laboratory, and subsequent offspring cocooned in skyscrapers never knowing their ancestry, no more than lab rats in a gilded cage.
Yet still infection took hold, the disease mutating to adapt to each new host.
The toxic clouds rose above the skyline.
There was no other choice now.